Online Calculator Helps Cattle Producers Determine ROI
for BRD Treatment and Control Options

Cattle producers are fully aware of the expenses that go into herd management – feeding, housing, transporting and marketing – and perhaps most important,
overall health care.

Considering that bovine respiratory disease (BRD) costs producers between $500 and $900 million annually1-4, treating and controlling it can
mean more to their bottom line. But, how can producers really know what kind of a return they’ll get on that investment, and which products are going to be
most cost-effective for their operations?

To help them answer those questions and more, there’s a online pricing calculator from
Merial, the manufacturer of ZACTRAN® (gamithromycin), a control and treatment product for BRD.

By providing specific information on their herd, producers can quickly determine which product will provide the biggest return on their investment.

“When we look at investments – and potential losses – in terms of millions of dollars, scrutinizing the impact of every dollar is critical to running a
profitable organization,” says Ron Tessman, DVM, veterinary services, Merial. “Supply and demand are not within the producers control but choosing the most
cost-effective health care option is, which is why this calculator can be so valuable for them.”

ZACTRAN is a member of the powerful macrolide drug class and works similarly to DRAXXIN® (tulathromycin) and other macrolides – but ZACTRAN
costs significantly less.2, 5

Clinical signs of BRD producers should watch for include, but are not limited to:

  • quick or labored breathing
  • gaunt appearance
  • nasal discharge
  • rough hair coat
  • dry muzzle
  • and depression.6

BRD is also often observed in calves following the first movement to group housing after weaning. 7 Studies have shown treatment of calves with
the appropriate antimicrobial at this first movement significantly reduces the incidence of BRD in the subsequent 60 days. 7 These calves grew
better, were more likely to survive to first lactation, were younger at first calving and were less likely to have calving difficulty. 7 Calves
with no BRD reported within 60 days after this control therapy also produced more milk on the first test day after calving.7

ZACTRAN has been proven to generate a 24-hour rapid response in treatment field trials in clinically ill cattle.1

Other benefits of ZACTRAN, as determined in BRD field trials, include:

· In treatment trials, the majority of clinically ill cattle treated with ZACTRAN recovered and stayed healthy for the 10-day study.1

· In control trials, the majority of lightweight, high-risk cattle treated with ZACTRAN stayed healthy for the 10-day study.2

Zactran PI

To learn more, visit


For use in cattle only. Do not treat cattle within 35 days of slaughter. Because a discard time in milk has not been established, do not use in female
dairy cattle 20 months of age or older, or in calves to be processed for veal. The effects of ZACTRAN on bovine reproductive performance, pregnancy and
lactation have not been determined.

About Merial

Merial is a world-leading, innovation-driven animal health company, providing a comprehensive range of products to enhance the health and well-being of a
wide range of animals. Merial employs 6,100 people and operates in more than 150 countries worldwide with over €2 billion of sales in 2014.

Merial is a Sanofi company.

For more information, please see

®MERIAL and ZACTRAN are registered trademarks of Merial. ©2015 Merial, Inc., Duluth, GA. All rights reserved. RUMIOTD1508 (05/14)

Sifferman RL, Wolff WA, Holste JE, et al. Field efficacy evaluation of gamithromycin for treatment of bovine respiratory disease in cattle at feedlots. Intern J Appl Res Vet Med. 2011;9(2):171-180.

Lechtenberg K, Daniels CS, Royer GC, et al. Field efficacy study of gamithromycin for the control of bovine respiratory disease in cattle at high risk of
developing the disease. Intern J Appl Res Vet Med. 2011;9(2):189-197.

Science Daily. Bovine Respiratory Disease: New Research to Tackle Major Concern for Cattle Industry. Available at: Accessed May 15,
2015. March 2010.

Schneider JM, Tait RG, Jr., Busby WD, Reecy JM. An evaluation of bovine respiratory disease complex in feedlot cattle: Impact on performance and carcass
traits using treatment records and lung lesion scores. J Anim Sci. 2009;87:1821-1827.

ZACTRAN product label.

Bagley CV. Bovine Respiratory Disease, Utah State University Cooperative Extension. 1997;4:1-4.

Stanton AL, Kelton DF, Leblanc SJ, Wormuth J, Leslie KE. The effect of respiratory disease and a preventative antibiotic treatment on growth, survival, age
at first calving, and milk production of dairy heifers. J. Dairy Sci. 2012;95:4950–4960.